Detecting long tandem duplications in genomic sequences
نویسندگان
چکیده
منابع مشابه
Statistical Approaches to Detecting and Analyzing Tandem Repeats in Genomic Sequences
Tandem repeats (TRs) are frequently observed in genomes across all domains of life. Evidence suggests that some TRs are crucial for proteins with fundamental biological functions and can be associated with virulence, resistance, and infectious/neurodegenerative diseases. Genome-scale systematic studies of TRs have the potential to unveil core mechanisms governing TR evolution and TR roles in sh...
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For a genomic region containing a tandem gene cluster, a proper set of alignments needs to align only orthologous segments, i.e., those separated by a speciation event. Otherwise, methods for finding regions under evolutionary selection will not perform properly. Conversely, the alignments should indicate every orthologous pair of genes or genomic segments. Attaining this goal in practice requi...
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SELECTION OF TANDEM DUPLICATIONS .................................................................. 478 Gene Dosage .............................................................................................................. 478 Coinheritance of Allelic Markers ............................................................................ 485 Operon Fusion ..... ............................... ...
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T H I S paper reports the successful induction by X rays of two tandem direct duplications for the lozenge region of the X chromosome of Drosophila. Numerous tandem direct duplications (ABAB) of spontaneous origin are now known in Drosophila: Bar, STURTEVANT (1925), MULLER, PROKOFYEVA-BELGOVSKAYA and KOSSIKOV (1936) and BRIDGES (1936); Hairy wing, DEMEREC and HOOVER ( 1939) ; Dp (2: 2) Star, LE...
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Large segmental duplications cover much of the Arabidopsis thaliana genome. Little is known about their origins. We show that they are primarily due to at least four different large-scale duplication events that occurred 100 to 200 million years ago, a formative period in the diversification of the angiosperms. A better understanding of the complex structural history of angiosperm genomes is ne...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2012
ISSN: 1471-2105
DOI: 10.1186/1471-2105-13-83